PEBP1

Across TCGA pan-cancer cohorts, PEBP1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of PEBP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where PEBP1 RNA is repressed in tumor relative to normal tissue. In most cancer types PEBP1 is over-expressed in tumor, although a few such as KIRP and THCA show the opposite, repressed pattern.

KIRP, THCA, and KICH are the cancer types where PEBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PEBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	IV	−1.452	<.001	11	view →
THCA	All	IV	−1.317	<.001	11	view →
KICH	Male	All	−2.026	<.001	10	view →
HNSC	Female	II,III,IV	−0.573	<.001	10	view →
LUAD	Female	III,IV	−1.108	<.001	9	view →
KIRC	Male	All	−1.025	<.001	9	view →
LUSC	All	All	−0.529	<.001	6	view →
CHOL	All	All	−1.243	<.001	3	view →
LIHC	Female	All	−0.427	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

PEBP1–KIRP

Open the KIRP breakdown →