PEA15

Across TCGA patient cohorts, PEA15 protein abundance is significantly associated with the RNA expression of many other genes, with 14,787 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEA15-associated genes across cancer lineages are COMP, CNRIP1, and DDR2. Each is linked with PEA15 in more than 7 cancer types. Because this analysis shows association rather than direction, both PEA15-to-partner and partner-to-PEA15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEA15 versus COMP in COAD, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEA15→partner) and Y-score (partner→PEA15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	COMP →	+1.950	+0.411	<.001	<.001	3	7
COAD	CNRIP1 →	+0.640	+0.532	<.001	<.001	3	7
COAD	DDR2 →	+1.043	+0.533	<.001	<.001	3	7
COAD	LMOD1 →	+1.165	+0.400	<.001	<.001	3	7
GBM	ZCCHC24 →	+0.971	+0.531	<.001	<.001	3	7
UCEC	PODN →	+0.910	+0.290	.004	.009	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,787 associations by consensus.

PEA15 vs COMP — COAD

Explore this scatter interactively →