PDZRN4

Across TCGA patient cohorts, PDZRN4 protein abundance is significantly associated with the protein abundance of many other proteins, with 373 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDZRN4-associated proteins across cancer lineages are CSNK1G2_S32, EML1_S113, and GRK5_S586. Each is linked with PDZRN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDZRN4-to-partner and partner-to-PDZRN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZRN4 versus CSNK1G2_S32 in GBM, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZRN4→partner) and Y-score (partner→PDZRN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CSNK1G2_S32 →	+0.483	+0.770	<.001	.002	3	1
GBM	EML1_S113 →	+1.003	+0.741	<.001	.001	3	1
GBM	GRK5_S586 →	+0.826	+0.953	.001	.003	3	1
GBM	IWS1_S400 →	-1.031	-0.504	<.001	.003	3	1
GBM	KANSL2 →	+0.377	+0.587	.001	<.001	3	1
GBM	ANKRD17_S2489 →	-0.543	-0.448	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 373 associations by consensus.

PDZRN4 vs CSNK1G2_S32 — GBM

Explore this scatter interactively →