PDZRN4

Across TCGA cell cohorts, PDZRN4 RNA expression is significantly associated with the RNA expression of many other genes, with 3,800 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PDZRN4-associated genes across cancer lineages are PKHD1, MARCKSL1, and AMBN. Each is linked with PDZRN4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PDZRN4-to-partner and partner-to-PDZRN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZRN4 versus PKHD1 in BONE, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZRN4→partner) and Y-score (partner→PDZRN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PKHD1 →	+0.880	+0.411	<.001	<.001	3	3
BONE	MARCKSL1 →	+2.633	+0.319	<.001	<.001	3	3
BONE	AMBN →	+1.021	+0.336	<.001	<.001	3	3
BONE	GAS1 →	+2.834	+0.346	<.001	<.001	3	3
BONE	TCF4 →	+1.954	+0.340	<.001	.002	3	3
SOFT_TISSUE	LRRC3B →	+0.173	+0.802	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,800 associations by consensus.

PDZRN4 vs PKHD1 — BONE

Explore this scatter interactively →