PDZK1IP1

Across TCGA patient cohorts, PDZK1IP1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,552 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PDZK1IP1-associated genes across cancer lineages are SLC5A1, LCN2, and FUT3. Each is linked with PDZK1IP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDZK1IP1-to-partner and partner-to-PDZK1IP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZK1IP1 versus SLC5A1 in OV, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZK1IP1→partner) and Y-score (partner→PDZK1IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLC5A1 →	+3.081	+1.504	<.001	<.001	3	6
UCEC	LCN2 →	+2.971	+1.299	<.001	<.001	3	5
BRCA	FUT3 →	+1.922	+0.882	.005	.003	3	5
OV	PRRG4 →	+1.391	+1.448	.001	.002	3	4
OV	GDF11 →	-1.577	-1.355	.003	.004	3	4
UCEC	SQOR →	+1.130	+1.178	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,552 associations by consensus.

PDZK1IP1 vs SLC5A1 — OV

Explore this scatter interactively →