PDZK1IP1

Across TCGA cell cohorts, PDZK1IP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,371 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PDZK1IP1-associated GO terms across cancer lineages are Regulation of hippocampal neuron apoptotic process, Negative regulation of hippocampal neuron apoptotic process, and Cellular response to tumor necrosis factor. Each is linked with PDZK1IP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PDZK1IP1-to-partner and partner-to-PDZK1IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippocampal neuron apoptotic process grouped by PDZK1IP1-low versus PDZK1IP1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZK1IP1→partner) and Y-score (partner→PDZK1IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of hippocampal neuron apoptotic process →	+1.766	+2.356	<.001	<.001	3	13
STOMACH	Negative regulation of hippocampal neuron apoptotic process →	+1.664	+2.356	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cellular response to tumor necrosis factor →	+0.078	+2.949	<.001	<.001	3	12
BREAST	Positive regulation of iron ion transport →	+1.523	+2.384	<.001	<.001	3	12
BREAST	Positive regulation of iron ion transmembrane transport →	+1.523	+2.384	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Antigen processing and presentation of peptide antigen via MHC class I →	+0.167	+2.889	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,371 associations by consensus.

Regulation of hippocampal neuron apoptotic process by PDZK1IP1 expression — STOMACH

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