PDZK1

Across TCGA cell cohorts, PDZK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,468 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PDZK1-associated GO terms across cancer lineages are Carnitine transmembrane transport, Carnitine transport, and Negative regulation of transforming growth factor beta production. Each is linked with PDZK1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PDZK1-to-partner and partner-to-PDZK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Carnitine transmembrane transport grouped by PDZK1-low versus PDZK1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZK1→partner) and Y-score (partner→PDZK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Carnitine transmembrane transport →	+0.981	+2.622	<.001	<.001	3	10
STOMACH	Carnitine transport →	+0.981	+2.622	<.001	<.001	3	10
OVARY	Negative regulation of transforming growth factor beta production →	+0.290	+2.390	<.001	<.001	3	9
BONE	Golgi vesicle transport →	+0.047	+0.466	<.001	.004	3	9
BONE	Protein localization to vacuole →	+0.101	+0.754	<.001	.003	3	8
OESOPHAGUS	Nuclear receptor-mediated signaling pathway →	+0.078	+0.752	.006	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,468 associations by consensus.

Carnitine transmembrane transport by PDZK1 expression — STOMACH

Explore this box plot interactively →