PDZD9

Across TCGA patient cohorts, PDZD9 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDZD9-associated genes across cancer lineages are GMP, Adipocytes, and pDC. Each is linked with PDZD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDZD9-to-partner and partner-to-PDZD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by PDZD9-low versus PDZD9-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD9→partner) and Y-score (partner→PDZD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	GMP →	+0.128	+3.758	<.001	.044	3	1
UCEC	Adipocytes →	+0.024	+2.337	.004	.010	3	1
UCEC	pDC →	+0.076	+3.354	.001	.005	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.129	.037	.019	2	1
UCEC	Th2 cells →	+0.175	+2.815	.045	.036	2	1
UCEC	Endothelial cells →	-0.041	-3.542	.026	.003	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GMP by PDZD9 expression — LIHC

Explore this box plot interactively →