PDZD9

Across TCGA cell cohorts, PDZD9 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,366 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PDZD9-associated GO terms across cancer lineages are Regulation of triglyceride storage, Peptide hormone processing, and Muscle filament sliding. Each is linked with PDZD9 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDZD9-to-partner and partner-to-PDZD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of triglyceride storage grouped by PDZD9-low versus PDZD9-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD9→partner) and Y-score (partner→PDZD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of triglyceride storage →	-1.165	-0.198	<.001	<.001	3	6
LUNG_SCLC	Peptide hormone processing →	-0.154	-0.159	.002	.006	3	5
BLOOD_Leukemia	Muscle filament sliding →	-0.118	-0.087	<.001	<.001	3	5
LUNG_SCLC	Positive regulation of vasculature development →	-0.053	-0.167	.005	.003	3	4
LUNG_SCLC	Response to acetaldehyde →	-1.039	-0.173	.001	<.001	3	4
LUNG_SCLC	Cellular response to acetaldehyde →	-1.039	-0.173	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,366 associations by consensus.

Regulation of triglyceride storage by PDZD9 expression — LUNG_SCLC

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