PDZD8

Across TCGA patient cohorts, PDZD8 protein abundance is significantly associated with the RNA expression of many other genes, with 6,597 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDZD8-associated genes across cancer lineages are APLF, COCH, and CEP128. Each is linked with PDZD8 in more than 3 cancer types. Because this analysis shows association rather than direction, both PDZD8-to-partner and partner-to-PDZD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZD8 versus APLF in CCRCC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD8→partner) and Y-score (partner→PDZD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	APLF →	-0.532	-0.231	<.001	<.001	3	3
HNSC	COCH →	-1.096	-0.330	<.001	<.001	3	3
UCEC	CEP128 →	-0.644	-0.466	<.001	<.001	3	3
UCEC	GINS1 →	-0.810	-0.375	<.001	.001	3	3
LUAD	C4BPA →	+1.762	+0.257	<.001	.002	3	3
LUAD	HROB →	-0.816	-0.207	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,597 associations by consensus.

PDZD8 vs APLF — CCRCC

Explore this scatter interactively →