PDYN

Across TCGA patient cohorts, PDYN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,579 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDYN-associated proteins across cancer lineages are CYFIP2, RPLP0, and HTT. Each is linked with PDYN in more than 3 cancer types. Because this analysis shows association rather than direction, both PDYN-to-partner and partner-to-PDYN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDYN versus CYFIP2 in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDYN→partner) and Y-score (partner→PDYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYFIP2 →	+0.415	+1.475	<.001	<.001	3	4
GBM	RPLP0 →	-0.308	-1.374	<.001	<.001	3	3
LUAD	HTT →	+0.181	+0.029	<.001	.001	3	3
GBM	SYNE1 →	+0.315	+1.642	<.001	<.001	3	3
LSCC	CARNMT1 →	-0.322	-0.035	.002	.004	3	3
GBM	ETF1 →	-0.232	-1.778	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,579 associations by consensus.

PDYN vs CYFIP2 — GBM

Explore this scatter interactively →