PDYN

Across TCGA patient cohorts, PDYN protein abundance is significantly associated with the RNA expression of many other genes, with 9,692 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDYN-associated genes across cancer lineages are PRODH, SLC25A1, and SEZ6L. Each is linked with PDYN in more than 1 cancer types. Because this analysis shows association rather than direction, both PDYN-to-partner and partner-to-PDYN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDYN versus PRODH in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDYN→partner) and Y-score (partner→PDYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.763	+0.938	<.001	<.001	3	1
GBM	SLC25A1 →	-0.267	-0.997	.008	.006	3	1
GBM	SEZ6L →	+1.162	+0.872	.002	<.001	3	1
GBM	SOX10 →	+1.402	+1.127	<.001	<.001	3	1
GBM	SEPTIN3 →	+0.831	+1.457	<.001	<.001	3	1
GBM	LMF2 →	-0.381	-1.181	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,692 associations by consensus.

PDYN vs PRODH — GBM

Explore this scatter interactively →