PDYN

Across TCGA patient cohorts, PDYN protein abundance is significantly associated with the protein abundance of many other proteins, with 29,074 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDYN-associated proteins across cancer lineages are RECQL, REEP1, and REEP1_S192. Each is linked with PDYN in more than 1 cancer types. Because this analysis shows association rather than direction, both PDYN-to-partner and partner-to-PDYN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDYN versus RECQL in GBM, with a Pearson correlation of -0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDYN→partner) and Y-score (partner→PDYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RECQL →	-0.233	-0.920	<.001	<.001	3	1
GBM	REEP1 →	+0.704	+1.447	<.001	<.001	3	1
GBM	REEP1_S192 →	+0.622	+1.087	<.001	<.001	3	1
GBM	REEP2 →	+0.312	+0.923	<.001	<.001	3	1
GBM	RELB →	-0.279	-0.863	<.001	<.001	3	1
GBM	RELCH →	+0.267	+1.313	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29,074 associations by consensus.

PDYN vs RECQL — GBM

Explore this scatter interactively →