PDYN

Across TCGA cell cohorts, PDYN RNA expression is significantly associated with the go_rna of many other GO terms, with 450 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PDYN-associated GO terms across cancer lineages are Regulation by virus of viral protein levels in host cell, Inner ear development, and Left/right pattern formation. Each is linked with PDYN in more than 3 cancer types. Because this analysis shows association rather than direction, both PDYN-to-partner and partner-to-PDYN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation by virus of viral protein levels in host cell grouped by PDYN-low versus PDYN-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDYN→partner) and Y-score (partner→PDYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation by virus of viral protein levels in host cell →	+0.132	+0.024	.001	.009	3	3
LUNG_NSCLC_LUAD	Inner ear development →	-0.035	-0.004	.006	.003	3	3
LUNG_NSCLC_LUAD	Left/right pattern formation →	-0.030	-0.003	.004	.009	3	3
LUNG_NSCLC_LUAD	Heterophilic cell-cell adhesion →	-0.143	-0.005	.002	.008	3	3
LUNG_NSCLC_LUAD	Determination of left/right symmetry →	-0.030	-0.003	.005	.007	3	3
LUNG_NSCLC_LUAD	DNA synthesis involved in DNA replication →	+0.042	+0.003	.005	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 450 associations by consensus.

Regulation by virus of viral protein levels in host cell by PDYN expression — SKIN

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