PDXP

Across TCGA cell cohorts, PDXP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,147 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PDXP-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Pyridoxal 5'-phosphate metabolic process, and Defense response to bacterium. Each is linked with PDXP in more than 15 cancer types. Because this analysis shows association rather than direction, both PDXP-to-partner and partner-to-PDXP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by PDXP-low versus PDXP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDXP→partner) and Y-score (partner→PDXP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DNA replication-dependent chromatin assembly →	+0.125	+1.149	.002	.002	3	16
URINARY_TRACT	Pyridoxal 5'-phosphate metabolic process →	+0.195	+2.034	.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.108	-0.977	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of tyrosine phosphorylation of STAT protein →	-0.176	-1.167	<.001	<.001	3	14
BONE	Cell-matrix adhesion →	-0.161	-1.130	.005	<.001	3	13
LARGE_INTESTINE	Autophagosome membrane docking →	-0.117	-1.161	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,147 associations by consensus.

DNA replication-dependent chromatin assembly by PDXP expression — LUNG_SCLC

Explore this box plot interactively →