PDSS2

Across TCGA patient cohorts, PDSS2 protein abundance is significantly associated with the protein abundance of many other proteins, with 13,295 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PDSS2-associated proteins across cancer lineages are QRSL1, MRPL44, and PTCD3. Each is linked with PDSS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PDSS2-to-partner and partner-to-PDSS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDSS2 versus QRSL1 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDSS2→partner) and Y-score (partner→PDSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	QRSL1 →	+0.390	+0.295	<.001	.001	3	7
UCEC	MRPL44 →	+0.423	+0.637	<.001	<.001	3	6
PDAC	PTCD3 →	+0.289	+0.286	<.001	<.001	3	6
BRCA	MRPS10 →	+0.400	+0.317	<.001	.005	2	6
UCEC	MRPS30 →	+0.337	+0.563	<.001	<.001	3	5
LUAD	MRPS31 →	+0.290	+0.376	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,295 associations by consensus.

PDSS2 vs QRSL1 — LSCC

Explore this scatter interactively →