PDSS2

Across TCGA cell cohorts, PDSS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,370 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDSS2-associated GO terms across cancer lineages are Ubiquinone metabolic process, Glutaminyl-tRNAGln biosynthesis via transamidation, and Quinone metabolic process. Each is linked with PDSS2 in more than 13 cancer types. Because this analysis shows association rather than direction, both PDSS2-to-partner and partner-to-PDSS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquinone metabolic process grouped by PDSS2-low versus PDSS2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDSS2→partner) and Y-score (partner→PDSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Ubiquinone metabolic process →	+0.105	+0.907	<.001	<.001	3	14
BREAST	Glutaminyl-tRNAGln biosynthesis via transamidation →	+0.108	+1.097	<.001	<.001	3	14
BREAST	Quinone metabolic process →	+0.116	+1.060	<.001	<.001	3	13
LARGE_INTESTINE	Quinone biosynthetic process →	+0.110	+0.931	<.001	<.001	3	13
LARGE_INTESTINE	Ubiquinone biosynthetic process →	+0.110	+0.931	<.001	<.001	3	13
BREAST	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.097	+0.984	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,370 associations by consensus.

Ubiquinone metabolic process by PDSS2 expression — LARGE_INTESTINE

Explore this box plot interactively →