PDSS2

Across TCGA cell cohorts, PDSS2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDSS2-associated genes across cancer lineages are OLIG3. Each is linked with PDSS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDSS2-to-partner and partner-to-PDSS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OLIG3 grouped by PDSS2-low versus PDSS2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDSS2→partner) and Y-score (partner→PDSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OLIG3 →	+0.024	+4.095	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OLIG3 by PDSS2 expression — LARGE_INTESTINE

Explore this box plot interactively →