PDP1

Across TCGA cell cohorts, PDP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,707 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PDP1-associated GO terms across cancer lineages are Positive regulation of exosomal secretion, Amino acid metabolic process, and Membrane tubulation. Each is linked with PDP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PDP1-to-partner and partner-to-PDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of exosomal secretion grouped by PDP1-low versus PDP1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDP1→partner) and Y-score (partner→PDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of exosomal secretion →	+0.117	+1.613	.001	<.001	3	13
LIVER	Amino acid metabolic process →	-0.089	-2.481	.002	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Membrane tubulation →	+0.101	+1.450	.001	.003	3	12
LARGE_INTESTINE	Regulation of protein localization to mitochondrion →	+0.118	+1.268	<.001	<.001	3	12
BREAST	Regulation of hippo signaling →	+0.067	+1.523	<.001	<.001	3	12
BONE	Regulation of plasminogen activation →	+0.293	+1.321	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,707 associations by consensus.

Positive regulation of exosomal secretion by PDP1 expression — SOFT_TISSUE

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