PDLIM7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDLIM7 mutation is significantly associated with the RNA expression of many other genes, with 2,135 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDLIM7-associated genes across cancer lineages are RNA5SP410, CDCA2, and PRC1. Each is linked with PDLIM7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PDLIM7-to-partner and partner-to-PDLIM7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM7→partner) and Y-score (partner→PDLIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP410 →+0.941+2.637<.001<.00133
UCECCDCA2 →+1.036+4.169<.001<.00132
UCECPRC1 →+0.848+3.616<.001.00132
COADMIR450A2 →+0.147+4.831<.001.00232
COADSNORD65C →+0.511+3.108<.001.00732
COADRNU6-130P →+1.126+2.852<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,135 associations by consensus.

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