Across TCGA pan-cancer cohorts, PDLIM7 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of PDLIM7’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PDLIM7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PDLIM7 is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.
HNSC, KIRC, and THCA are the cancer types where PDLIM7 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PDLIM7 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.