Across TCGA cell cohorts, PDLIM7 mutation is significantly associated with the RNA expression of many other genes, with 329 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDLIM7-associated genes across cancer lineages are OR2D3, NUTM1, and C2orf78. Each is linked with PDLIM7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PDLIM7-to-partner and partner-to-PDLIM7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM7→partner) and Y-score (partner→PDLIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2D3 →	+0.043	+4.481	<.001	.001	3	3
LARGE_INTESTINE	NUTM1 →	+0.061	+2.894	<.001	.002	3	2
BONE	C2orf78 →	+0.045	+3.169	.004	.004	3	2
BONE	BPIFA1 →	+0.241	+3.544	<.001	.002	3	2
BONE	SFTPA1 →	+0.089	+3.700	.002	.003	3	1
BONE	CRISP2 →	+0.064	+3.415	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 329 associations by consensus.

Exploration

PDLIM7 survival (RNA) · tumor vs normal (RNA) · all PDLIM7 data types