PDLIM4

Across TCGA patient cohorts, PDLIM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,180 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PDLIM4-associated proteins across cancer lineages are GPX8, MMP14, and PDLIM4_S112. Each is linked with PDLIM4 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDLIM4-to-partner and partner-to-PDLIM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDLIM4 versus GPX8 in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM4→partner) and Y-score (partner→PDLIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GPX8 →	+0.759	+1.441	<.001	<.001	3	6
GBM	MMP14 →	+0.655	+2.045	<.001	<.001	3	6
COAD	PDLIM4_S112 →	+0.641	+1.039	<.001	<.001	3	6
BRCA	CRTAP →	+0.486	+1.120	.001	<.001	3	5
OV	FAP →	+1.000	+1.108	<.001	<.001	3	5
COAD	MRC2 →	+0.513	+0.890	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,180 associations by consensus.

PDLIM4 vs GPX8 — GBM

Explore this scatter interactively →