PDLIM4

Across TCGA patient cohorts, PDLIM4 protein abundance is significantly associated with the RNA expression of many other genes, with 14,771 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDLIM4-associated genes across cancer lineages are MYL9, LOXL1, and TAGLN. Each is linked with PDLIM4 in more than 9 cancer types. Because this analysis shows association rather than direction, both PDLIM4-to-partner and partner-to-PDLIM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDLIM4 versus MYL9 in UCEC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM4→partner) and Y-score (partner→PDLIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.430	+0.772	<.001	<.001	3	10
OV	LOXL1 →	+1.446	+0.727	<.001	<.001	3	10
OV	TAGLN →	+1.561	+0.596	<.001	<.001	3	10
BRCA	COL1A2 →	+1.960	+0.705	<.001	<.001	3	10
OV	CCN4 →	+1.567	+0.649	<.001	<.001	3	9
OV	MEIS3 →	+1.397	+0.746	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,771 associations by consensus.

PDLIM4 vs MYL9 — UCEC

Explore this scatter interactively →