PDLIM4

Across TCGA patient cohorts, PDLIM4 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,367 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PDLIM4-associated proteins across cancer lineages are RCN3, TAGLN, and PDLIM4_S112. Each is linked with PDLIM4 in more than 9 cancer types. Because this analysis shows association rather than direction, both PDLIM4-to-partner and partner-to-PDLIM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDLIM4 versus RCN3 in COAD, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM4→partner) and Y-score (partner→PDLIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RCN3 →	+0.782	+0.581	<.001	<.001	3	10
COAD	TAGLN →	+1.370	+0.779	<.001	<.001	3	10
COAD	PDLIM4_S112 →	+0.745	+0.777	<.001	<.001	3	10
UCEC	PDLIM7 →	+1.203	+1.096	<.001	<.001	3	10
COAD	MYL6 →	+0.578	+0.702	<.001	<.001	3	10
UCEC	MYL9 →	+1.257	+1.078	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,367 associations by consensus.

PDLIM4 vs RCN3 — COAD

Explore this scatter interactively →