PDLIM4

Across TCGA cell cohorts, PDLIM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,445 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PDLIM4-associated GO terms across cancer lineages are Excitatory chemical synaptic transmission, Regulation of cell-substrate junction assembly, and Viral process. Each is linked with PDLIM4 in more than 14 cancer types. Because this analysis shows association rather than direction, both PDLIM4-to-partner and partner-to-PDLIM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Excitatory chemical synaptic transmission grouped by PDLIM4-low versus PDLIM4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDLIM4→partner) and Y-score (partner→PDLIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Excitatory chemical synaptic transmission →	+1.309	+2.459	<.001	<.001	3	15
BONE	Regulation of cell-substrate junction assembly →	+0.208	+3.090	<.001	<.001	3	11
BONE	Viral process →	+0.102	+3.032	<.001	<.001	3	11
OESOPHAGUS	Regulation of fibroblast proliferation →	+0.120	+3.041	<.001	.001	3	11
BONE	Regulation of focal adhesion assembly →	+0.208	+3.090	<.001	<.001	3	11
BONE	Response to acid chemical →	+0.080	+2.284	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,445 associations by consensus.

Excitatory chemical synaptic transmission by PDLIM4 expression — OVARY

Explore this box plot interactively →