PDK3

Across TCGA patient cohorts, PDK3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,776 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDK3-associated genes across cancer lineages are SNRPEP9, MBTPS2, and LNPK. Each is linked with PDK3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDK3-to-partner and partner-to-PDK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDK3 versus SNRPEP9 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDK3→partner) and Y-score (partner→PDK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPEP9 →	+1.031	+0.597	<.001	<.001	3	6
UCEC	MBTPS2 →	+0.612	+0.511	.003	<.001	3	4
OV	LNPK →	+0.532	+0.550	.001	<.001	3	4
CCRCC	GIMAP8 →	-0.545	-0.345	.009	.008	3	4
HNSC	YY2 →	+0.451	+0.342	<.001	<.001	3	4
UCEC	SCML1 →	+1.324	+0.496	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,776 associations by consensus.

PDK3 vs SNRPEP9 — UCEC

Explore this scatter interactively →