PDILT

Across TCGA patient cohorts, PDILT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,170 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible PDILT-associated GO terms across cancer lineages are Methionine metabolic process, Cellular response to unfolded protein, and Endoplasmic reticulum organization. Each is linked with PDILT in more than 10 cancer types. Because this analysis shows association rather than direction, both PDILT-to-partner and partner-to-PDILT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methionine metabolic process grouped by PDILT-low versus PDILT-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDILT→partner) and Y-score (partner→PDILT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Methionine metabolic process →	+0.033	+0.049	<.001	<.001	3	10
ESCA	Cellular response to unfolded protein →	+0.069	+0.121	<.001	.002	2	11
STAD	Endoplasmic reticulum organization →	+0.091	+0.344	<.001	<.001	3	9
STAD	Vacuole organization →	+0.088	+0.289	<.001	.007	2	10
STAD	Endoplasmic reticulum unfolded protein response →	+0.100	+0.401	<.001	<.001	2	10
STAD	Monosaccharide metabolic process →	+0.084	+0.292	<.001	.003	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,170 associations by consensus.

Methionine metabolic process by PDILT expression — KIRC

Explore this box plot interactively →