PDILT

Across TCGA pan-cancer cohorts, PDILT RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated PDILT data layer compared with 11 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PDILT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDILT expression acts as an unfavorable survival marker, although some lineages such as GBM and KIRP show a favorable association.

UCEC, CESC, and SKCM are the cancer types where PDILT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.735	0.862	<.001	72	view →
CESC	OS	Tertile	IV	0.091	0.593	<.001	36	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	34	view →
CHOL	DFS	Median	II,III,IV	0.121	0.626	.002	31	view →
COAD	DFS	Tertile	II,III,IV	0.492	0.757	.004	30	view →
GBM	OS	Tertile	All	0.516	0.365	.009	24	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	21	view →
THYM	DFS	Tertile	All	0.238	0.748	.005	12	view →
KIRP	DFS	Tertile	III,IV	1.000	0.381	.048	8	view →
UVM	DFS	Tertile	All	1.000	0.408	.046	6	view →
BRCA	DFS	Tertile	IV	0.989	0.583	.014	6	view →
PRAD	DFS	Median	All	0.960	0.907	.004	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

PDILT–UCEC (DFS)

Open the UCEC breakdown →