PDILT

Across TCGA cell cohorts, PDILT RNA expression is significantly associated with the mutation status of many other genes, with 64 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDILT-associated genes across cancer lineages are MT-ND1, NECTIN1, and PRDM5. Each is linked with PDILT in more than 1 cancer types. Because this analysis shows association rather than direction, both PDILT-to-partner and partner-to-PDILT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT-ND1 grouped by PDILT-low versus PDILT-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDILT→partner) and Y-score (partner→PDILT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	MT-ND1 →	+4.357	+0.057	.006	<.001	3	2
PANCREAS	NECTIN1 →	+4.614	+0.005	.004	<.001	3	1
PANCREAS	PRDM5 →	+4.614	+0.005	.004	<.001	3	1
PANCREAS	EP400 →	+4.029	+0.004	.007	<.001	3	1
PANCREAS	LRRC8B →	+5.614	+0.006	.002	<.001	3	1
KIDNEY	PDCD5 →	+5.000	+0.013	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

MT-ND1 by PDILT expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →