PDIK1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDIK1L mutation is significantly associated with the RNA expression of many other genes, with 2,148 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDIK1L-associated genes across cancer lineages are RN7SL134P, RNU6-1064P, and RN7SL447P. Each is linked with PDIK1L in more than 2 cancer types. Because this analysis shows association rather than direction, both PDIK1L-to-partner and partner-to-PDIK1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by PDIK1L-low versus PDIK1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDIK1L→partner) and Y-score (partner→PDIK1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL134P →+0.110+2.277<.001<.00133
UCECRNU6-1064P →+0.340+1.532.008.00432
CESCRN7SL447P →+0.163+5.201<.001.00732
CESCLINC02559 →+1.780+6.342<.001.00132
UCECNDUFAF2P1 →+0.618+2.439<.001.00331
UCECAQP7P3 →+0.025+2.997<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,148 associations by consensus.

RN7SL134P by PDIK1L expression — UCEC

Box plot of RN7SL134P in PDIK1L-low vs PDIK1L-high samples in UCEC.

Explore this box plot interactively →

Exploration