PDIK1L

Across TCGA cell cohorts, PDIK1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,782 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDIK1L-associated GO terms across cancer lineages are Negative regulation of G2/MI transition of meiotic cell cycle, Regulation of G2/MI transition of meiotic cell cycle, and Extracellular matrix organization. Each is linked with PDIK1L in more than 17 cancer types. Because this analysis shows association rather than direction, both PDIK1L-to-partner and partner-to-PDIK1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of G2/MI transition of meiotic cell cycle grouped by PDIK1L-low versus PDIK1L-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDIK1L→partner) and Y-score (partner→PDIK1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of G2/MI transition of meiotic cell cycle →	+0.164	+1.211	<.001	<.001	3	18
BONE	Regulation of G2/MI transition of meiotic cell cycle →	+0.209	+1.337	<.001	<.001	3	16
BONE	Extracellular matrix organization →	-0.148	-0.691	.003	<.001	3	14
BONE	Extracellular structure organization →	-0.148	-0.691	.003	<.001	3	14
BONE	External encapsulating structure organization →	-0.148	-0.648	.003	.001	3	13
STOMACH	Regulation of mitotic centrosome separation →	+0.154	+0.967	.004	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,782 associations by consensus.

Negative regulation of G2/MI transition of meiotic cell cycle by PDIK1L expression — LUNG_SCLC

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