PDHA1

Across TCGA patient cohorts, PDHA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,903 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDHA1-associated proteins across cancer lineages are RBBP7, WDHD1, and PDS5A_T1208. Each is linked with PDHA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDHA1-to-partner and partner-to-PDHA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDHA1 versus RBBP7 in BRCA, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDHA1→partner) and Y-score (partner→PDHA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBBP7 →	+0.428	+0.637	<.001	<.001	3	6
LSCC	WDHD1 →	+0.658	+0.552	<.001	<.001	3	6
OV	PDS5A_T1208 →	+0.856	+0.533	.003	.002	3	6
OV	POLA1 →	+0.391	+0.518	<.001	<.001	3	6
LSCC	POLA1_T219 →	+0.861	+0.473	<.001	<.001	3	6
OV	PRIM2 →	+0.456	+0.789	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,903 associations by consensus.

PDHA1 vs RBBP7 — BRCA

Explore this scatter interactively →