PDGFRA

Across TCGA cell cohorts, PDGFRA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,843 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PDGFRA-associated GO terms across cancer lineages are Metanephric glomerulus morphogenesis, Metanephric glomerulus vasculature morphogenesis, and Metanephric glomerular capillary formation. Each is linked with PDGFRA in more than 12 cancer types. Because this analysis shows association rather than direction, both PDGFRA-to-partner and partner-to-PDGFRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metanephric glomerulus morphogenesis grouped by PDGFRA-low versus PDGFRA-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFRA→partner) and Y-score (partner→PDGFRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Metanephric glomerulus morphogenesis →	+1.610	+4.237	<.001	<.001	3	13
STOMACH	Metanephric glomerulus vasculature morphogenesis →	+1.610	+4.237	<.001	<.001	3	13
STOMACH	Metanephric glomerular capillary formation →	+1.610	+4.237	<.001	<.001	3	13
BONE	Luteinization →	+1.142	+2.470	<.001	.001	3	10
BLOOD_Lymphoma	Response to molecule of fungal origin →	-1.049	-1.144	<.001	<.001	3	9
BLOOD_Lymphoma	Cellular response to molecule of fungal origin →	-1.049	-1.144	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,843 associations by consensus.

Metanephric glomerulus morphogenesis by PDGFRA expression — STOMACH

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