Across TCGA patient cohorts, PDGFA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,832 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDGFA-associated proteins across cancer lineages are CLIP2, PPFIBP1, and DOCK1. Each is linked with PDGFA in more than 7 cancer types. Because this analysis shows association rather than direction, both PDGFA-to-partner and partner-to-PDGFA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFA→partner) and Y-score (partner→PDGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CLIP2 →	+0.730	+1.211	<.001	<.001	3	8
BRCA	PPFIBP1 →	+0.451	+0.801	<.001	<.001	3	7
BRCA	DOCK1 →	+0.348	+0.941	<.001	<.001	3	6
CCRCC	ARHGEF17 →	+0.307	+0.553	<.001	<.001	3	6
LSCC	FMNL3 →	+0.377	+0.926	<.001	<.001	3	6
OV	CLEC11A →	+0.730	+0.782	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,832 associations by consensus.

Exploration

PDGFA survival (RNA) · tumor vs normal (RNA) · all PDGFA data types