Across TCGA patient cohorts, PDGFA protein abundance is significantly associated with the protein abundance of many other proteins, with 6,156 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDGFA-associated proteins across cancer lineages are DHX37, SHROOM2_S1297, and LAMA2. Each is linked with PDGFA in more than 2 cancer types. Because this analysis shows association rather than direction, both PDGFA-to-partner and partner-to-PDGFA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFA→partner) and Y-score (partner→PDGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DHX37 →	-0.387	-2.195	<.001	<.001	3	3
GBM	SHROOM2_S1297 →	+0.755	+1.199	<.001	<.001	3	3
LSCC	LAMA2 →	+0.700	+1.092	<.001	<.001	3	2
GBM	LRP1 →	+0.337	+0.762	<.001	.001	2	3
LSCC	MB21D2 →	+0.417	+0.692	<.001	<.001	3	2
LSCC	MFAP2 →	+0.680	+0.915	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,156 associations by consensus.

Exploration

PDGFA survival (RNA) · tumor vs normal (RNA) · all PDGFA data types