PDE7B

Across TCGA patient cohorts, PDE7B protein abundance is significantly associated with the RNA expression of many other genes, with 722 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDE7B-associated genes across cancer lineages are ASF1A, CDC40, and CXCR2. Each is linked with PDE7B in more than 1 cancer types. Because this analysis shows association rather than direction, both PDE7B-to-partner and partner-to-PDE7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE7B versus ASF1A in LSCC, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE7B→partner) and Y-score (partner→PDE7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ASF1A →	-0.694	-1.504	<.001	<.001	3	2
LSCC	CDC40 →	-0.673	-1.396	.004	.002	3	2
LSCC	CXCR2 →	+2.340	+2.385	.003	.001	3	2
LSCC	MIR3657 →	-1.056	-1.495	.008	.003	3	2
LSCC	ARMCX5-GPRASP2 →	-0.580	-1.454	<.001	.001	3	2
UCEC	EIF3E →	-0.754	-0.562	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 722 associations by consensus.

PDE7B vs ASF1A — LSCC

Explore this scatter interactively →