Across TCGA cell cohorts, PDE6G RNA expression is significantly associated with the go_rna of many other GO terms, with 1,998 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PDE6G-associated GO terms across cancer lineages are Autophagy of mitochondrion, Regulation of establishment of T cell polarity, and Negative regulation of intrinsic apoptotic signaling pathway. Each is linked with PDE6G in more than 6 cancer types. Because this analysis shows association rather than direction, both PDE6G-to-partner and partner-to-PDE6G results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE6G→partner) and Y-score (partner→PDE6G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Autophagy of mitochondrion →	+0.065	+0.385	<.001	<.001	3	7
KIDNEY	Regulation of establishment of T cell polarity →	+0.224	+0.552	<.001	.002	3	7
BONE	Negative regulation of intrinsic apoptotic signaling pathway →	+0.078	+0.508	.006	.004	2	7
SOFT_TISSUE	Protein K63-linked ubiquitination →	+0.046	+0.412	.001	.005	3	6
SOFT_TISSUE	Maintenance of protein localization in organelle →	+0.092	+0.467	<.001	<.001	3	6
OESOPHAGUS	Regulation of macroautophagy →	+0.083	+0.320	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,998 associations by consensus.

Exploration

PDE6G survival (RNA) · tumor vs normal (RNA) · all PDE6G data types