Across TCGA pan-cancer cohorts, PDE6G RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PDE6G data layer.
The strongest signal is observed in uveal melanoma (UVM), where higher PDE6G RNA is associated with better overall survival. In most high-consensus cancer types, elevated PDE6G expression acts as an unfavorable survival marker, although some lineages such as UVM and HNSC show a favorable association.
UVM, HNSC, and LGG are the cancer types where PDE6G RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.