PDE6D

Across TCGA patient cohorts, PDE6D RNA expression is significantly associated with the protein abundance of many other proteins, with 14,738 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDE6D-associated proteins across cancer lineages are HERPUD1, DIS3L2, and CAMSAP2_S599. Each is linked with PDE6D in more than 3 cancer types. Because this analysis shows association rather than direction, both PDE6D-to-partner and partner-to-PDE6D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE6D versus HERPUD1 in HNSC, with a Pearson correlation of -0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE6D→partner) and Y-score (partner→PDE6D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HERPUD1 →	-0.533	-0.449	<.001	.001	3	4
GBM	DIS3L2 →	+0.195	+0.309	.001	<.001	3	4
GBM	CAMSAP2_S599 →	+0.475	+0.362	<.001	<.001	3	4
HNSC	GMPPB →	-0.287	-0.412	<.001	<.001	3	4
LUAD	ALG5 →	-0.344	-0.334	.001	.001	3	4
LUAD	WDR55_S14 →	-0.421	-0.271	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,738 associations by consensus.

PDE6D vs HERPUD1 — HNSC

Explore this scatter interactively →