PDE6C

Across TCGA patient cohorts, PDE6C RNA expression is significantly associated with the protein abundance of many other proteins, with 10,956 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDE6C-associated proteins across cancer lineages are ADO, SETMAR, and CCAR1. Each is linked with PDE6C in more than 4 cancer types. Because this analysis shows association rather than direction, both PDE6C-to-partner and partner-to-PDE6C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE6C versus ADO in BRCA, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE6C→partner) and Y-score (partner→PDE6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADO →	+0.194	+0.318	.008	.001	3	5
OV	SETMAR →	+0.331	+0.428	<.001	.003	3	4
HNSC	CCAR1 →	+0.168	+0.381	<.001	<.001	3	4
HNSC	GABPB1 →	+0.355	+0.457	<.001	.002	3	4
BRCA	GFPT1 →	-0.464	-0.397	<.001	<.001	3	4
CCRCC	SEC24A →	-0.390	-0.348	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,956 associations by consensus.

PDE6C vs ADO — BRCA

Explore this scatter interactively →