PDE6B-AS1

Across TCGA patient cohorts, PDE6B-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,119 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PDE6B-AS1-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Base-excision repair, and ATP biosynthetic process. Each is linked with PDE6B-AS1 in more than 25 cancer types. Because this analysis shows association rather than direction, both PDE6B-AS1-to-partner and partner-to-PDE6B-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by PDE6B-AS1-low versus PDE6B-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE6B-AS1→partner) and Y-score (partner→PDE6B-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of double-strand break repair →	+0.058	+0.160	.001	<.001	3	25
ESCA	Base-excision repair →	+0.060	+0.143	.001	<.001	3	25
STAD	ATP biosynthetic process →	+0.049	+0.060	<.001	<.001	3	25
ESCA	Positive regulation of DNA repair →	+0.056	+0.147	.002	.001	3	25
ESCA	tRNA processing →	+0.049	+0.154	.007	<.001	1	26
KIRC	Regulation of protein folding →	+0.060	+0.223	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,119 associations by consensus.

Positive regulation of double-strand break repair by PDE6B-AS1 expression — ESCA

Explore this box plot interactively →