PDE4DIP

Across TCGA patient cohorts, PDE4DIP RNA expression is significantly associated with the protein abundance of many other proteins, with 18,034 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PDE4DIP-associated proteins across cancer lineages are LRPPRC, UTP11, and DDX28. Each is linked with PDE4DIP in more than 5 cancer types. Because this analysis shows association rather than direction, both PDE4DIP-to-partner and partner-to-PDE4DIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE4DIP versus LRPPRC in LSCC, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE4DIP→partner) and Y-score (partner→PDE4DIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LRPPRC →	-0.478	-0.409	<.001	.006	3	6
LSCC	UTP11 →	-0.470	-0.406	<.001	.002	3	5
LSCC	DDX28 →	-0.565	-0.601	<.001	<.001	3	5
LSCC	HSPD1 →	-0.466	-0.347	<.001	.005	2	6
LSCC	PTCD3 →	-0.395	-0.593	<.001	<.001	3	5
LSCC	ACAD9 →	-0.428	-0.467	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,034 associations by consensus.

PDE4DIP vs LRPPRC — LSCC

Explore this scatter interactively →