PDE3A

Across TCGA patient cohorts, PDE3A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,058 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDE3A-associated proteins across cancer lineages are PDE3A_S312, PDE3A_S520, and PDE3A_S654. Each is linked with PDE3A in more than 9 cancer types. Because this analysis shows association rather than direction, both PDE3A-to-partner and partner-to-PDE3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE3A versus PDE3A_S312 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE3A→partner) and Y-score (partner→PDE3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PDE3A_S312 →	+1.176	+1.289	<.001	<.001	3	10
LUAD	PDE3A_S520 →	+1.205	+1.494	<.001	<.001	3	8
LUAD	PDE3A_S654 →	+0.691	+1.000	<.001	.001	3	7
OV	PDE3A_S570 →	+1.249	+1.615	.002	<.001	3	7
COAD	MYLK →	+0.574	+0.726	.001	.001	3	6
BRCA	NID1 →	+0.472	+0.558	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,058 associations by consensus.

PDE3A vs PDE3A_S312 — OV

Explore this scatter interactively →