Across TCGA patient cohorts, PDE2A RNA expression is significantly associated with the RNA expression of many other genes, with 18,754 significant associations in total. THYM shows the largest number of these associations.

The most reproducible PDE2A-associated genes across cancer lineages are LINC01537, AOC3, and GPIHBP1. Each is linked with PDE2A in more than 32 cancer types. Because this analysis shows association rather than direction, both PDE2A-to-partner and partner-to-PDE2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE2A→partner) and Y-score (partner→PDE2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	LINC01537 →	+2.071	+3.988	<.001	<.001	3	33
ACC	AOC3 →	+2.150	+2.409	<.001	<.001	3	31
SARC	GPIHBP1 →	+2.066	+1.032	<.001	<.001	3	30
ACC	LDB2 →	+1.883	+3.268	<.001	<.001	3	30
KIRC	S1PR1 →	+1.779	+1.796	<.001	<.001	3	30
KIRC	TEK →	+1.891	+1.770	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,754 associations by consensus.

Exploration

PDE2A survival (RNA) · tumor vs normal (RNA) · all PDE2A data types