Across TCGA cell cohorts, PDE2A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,495 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDE2A-associated GO terms across cancer lineages are Regulation of protein localization to Cajal body, Positive regulation of protein localization to Cajal body, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with PDE2A in more than 7 cancer types. Because this analysis shows association rather than direction, both PDE2A-to-partner and partner-to-PDE2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE2A→partner) and Y-score (partner→PDE2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein localization to Cajal body →	+0.065	+1.073	<.001	.008	3	8
STOMACH	Positive regulation of protein localization to Cajal body →	+0.065	+1.073	<.001	.008	3	8
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.116	+0.914	.001	.005	3	8
STOMACH	Glycogen catabolic process →	+0.138	+1.630	<.001	.004	3	8
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.130	+0.922	.002	.002	3	8
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.126	+0.867	.002	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,495 associations by consensus.

Exploration

PDE2A survival (RNA) · tumor vs normal (RNA) · all PDE2A data types