PDE1A

Across TCGA patient cohorts, PDE1A RNA expression is significantly associated with the RNA expression of many other genes, with 15,716 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible PDE1A-associated genes across cancer lineages are SELP, TEK, and GUCY1A2. Each is linked with PDE1A in more than 28 cancer types. Because this analysis shows association rather than direction, both PDE1A-to-partner and partner-to-PDE1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE1A versus SELP in STAD, with a Pearson correlation of 0.78.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE1A→partner) and Y-score (partner→PDE1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	SELP →	+1.797	+1.219	<.001	<.001	3	29
PAAD	TEK →	+1.363	+1.277	<.001	<.001	3	29
KIRC	GUCY1A2 →	+0.947	+1.014	<.001	<.001	3	29
UCS	TMEM47 →	+1.982	+1.184	<.001	<.001	3	28
STAD	GUCY1A1 →	+2.086	+1.322	<.001	<.001	3	28
CHOL	PRKG1 →	+1.431	+1.280	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,716 associations by consensus.

PDE1A vs SELP — STAD

Explore this scatter interactively →