PDCL

Across TCGA cell cohorts, PDCL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,977 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDCL-associated GO terms across cancer lineages are mRNA export from nucleus, mRNA transport, and RNA localization. Each is linked with PDCL in more than 19 cancer types. Because this analysis shows association rather than direction, both PDCL-to-partner and partner-to-PDCL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA export from nucleus grouped by PDCL-low versus PDCL-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCL→partner) and Y-score (partner→PDCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	mRNA export from nucleus →	+0.121	+0.924	<.001	<.001	3	20
SOFT_TISSUE	mRNA transport →	+0.107	+0.813	<.001	<.001	3	19
STOMACH	RNA localization →	+0.094	+0.706	.005	.004	3	19
BONE	Nucleic acid transport →	+0.100	+0.628	<.001	<.001	3	18
BONE	RNA transport →	+0.100	+0.628	<.001	<.001	3	18
BONE	Establishment of RNA localization →	+0.099	+0.746	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,977 associations by consensus.

mRNA export from nucleus by PDCL expression — SOFT_TISSUE

Explore this box plot interactively →