PDCD7

Across TCGA cell cohorts, PDCD7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,340 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDCD7-associated GO terms across cancer lineages are Regulation of heterochromatin organization, RNA splicing, via transesterification reactions, and Signal transduction in response to DNA damage. Each is linked with PDCD7 in more than 11 cancer types. Because this analysis shows association rather than direction, both PDCD7-to-partner and partner-to-PDCD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heterochromatin organization grouped by PDCD7-low versus PDCD7-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD7→partner) and Y-score (partner→PDCD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of heterochromatin organization →	+0.092	+0.910	<.001	<.001	3	12
BLOOD_Lymphoma	RNA splicing, via transesterification reactions →	+0.049	+0.489	<.001	.001	3	12
BLOOD_Leukemia	Signal transduction in response to DNA damage →	+0.047	+0.461	<.001	.001	3	12
PANCREAS	mRNA catabolic process →	+0.041	+0.457	<.001	.007	3	12
BLOOD_Lymphoma	Nucleic acid transport →	+0.090	+0.664	<.001	<.001	3	12
BLOOD_Lymphoma	RNA transport →	+0.090	+0.664	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,340 associations by consensus.

Regulation of heterochromatin organization by PDCD7 expression — OVARY

Explore this box plot interactively →