PDCD7

Across TCGA pan-cancer cohorts, PDCD7 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PDCD7 data layer compared with 3 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher PDCD7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDCD7 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PAAD show a favorable association.

KIRP, KICH, and LIHC are the cancer types where PDCD7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	All	0.737	0.949	<.001	93	view →
KICH	OS	Tertile	III,IV	0.256	1.000	.001	89	view →
LIHC	DFS	Quartile	All	0.392	0.565	.002	46	view →
UVM	DFS	Median	III,IV	0.208	0.740	.006	45	view →
ACC	DFS	Quartile	All	0.275	0.856	<.001	29	view →
LGG	OS	Tertile	All	0.696	0.892	.001	26	view →
COAD	DFS	Median	IV	0.278	0.658	.010	25	view →
UCEC	DFS	Quartile	III,IV	0.913	0.709	.001	24	view →
PAAD	DFS	Tertile	II,III,IV	0.561	0.333	<.001	20	view →
THYM	DFS	Quartile	All	1.000	0.835	.008	18	view →
SCLC	OS	Quartile	III,IV	0.773	0.279	.001	18	view →
OV	DFS	Tertile	All	0.449	0.357	.009	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PDCD7–KIRP (DFS)

Open the KIRP breakdown →